Baclofen (Lioresal) is an antidepressant and muscle relaxant. Baclofen is active substance of Lioresal. There are two dosage forms of Baclofen: Lioresal 10mg and Lioresal 20mg.

Baclofen (Lioresal) is administered in the treatment of spinal diseases (of traumatic, tumors, degenerative and infectious genesis), multiple sclerosis, traumatic brain injury, infantile cerebral palsy, strokes. In addition, Baclofen (Lioresal) is used in alcoholism treatment (affective disorders).

Baclofen (Lioresal) is contraindicated to patients, suffering from Parkinson’s disease, psychosis, chronic renal failure, hypersensitivity and epilepsy. There are also less dangerous contraindications, when Baclofen (Lioresal) can be carefully taken:

• peptic ulcer;
• cerebral atherosclerosis;
• cerebrovascular insufficiency.

Children under 12 years and elderly people should take Baclofen only under constant medical supervision. Pregnant and breastfeeding women should not take Baclofen (Lioresal).

You should take Baclofen (Lioresal) by mouth 3 times a day equal doses during food. Initial dose of Baclofen (Lioresal) should not exceed 15mg/ day. During treatment, the dosage should be gradually increased every 3-5 day to achieve the optimal dose. For adults, maximum dose of Baclofen (Lioresal) is 100mg/ day. If it is necessary to stop taking Baclofen (Lioresal), you should gradually reduce the dose during 1-2 weeks in order to avoid withdrawal syndrome.

Baclofen (Lioresal) can cause side effects, such as: confusion, dizziness, gait disturbance, hallucinations, depression, euphoria, apathy and other mood changes, nausea, vomiting, diarrhea or constipation, dry mouth, tremor, convulsions and some others.

Hepatic dysfunction can become the consequences of prolonged Baclofen (Lioresal) use.

If one of the above symptoms worries you while taking Baclofen (Lioresal), you should immediatelly inform your doctor.

Baclofen (Lioresal) overdose can lead to severe problems with health, including confusion, inhibition of respiratory center, muscular hypotonia and even coma.

Be sure to contact the doctor before to start taking Baclofen (Lioresal).

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